Correlative force and tip-enhanced Raman microscopy
نویسندگان
چکیده
منابع مشابه
Tip-Enhanced Raman Scattering
Background The ability to identify small quantities of adsorbed analyte or structural features down to the few-molecule level is a key challenge in nanotechnology. Optical spectroscopy provides an attractive means to achieve such identification via noninvasive implementations and the potential for chemical sensitivity. Raman scattering has emerged as a particularly powerful technique due to its...
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Atomic force microscopy (AFM) has evolved from the originally morphological imaging technique to a powerful and multifunctional technique for manipulating and detecting the interactions between molecules at nanometer resolution. However, AFM cannot provide the precise information of synchronized molecular groups and has many shortcomings in the aspects of determining the mechanism of the intera...
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Background The ability to identify small quantities of adsorbed analyte or structural features down to the few-molecule level is a key challenge in nanotechnology. Optical spectroscopy provides an attractive means to achieve such identification via non-invasive implementations and the potential for chemical sensitivity. Raman scattering has emerged as a particularly powerful technique due to it...
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This review provides a detailed overview of the state of the art in tip-enhanced Raman spectroscopy (TERS) and focuses on its applications at the horizon including those in materials science, chemical science and biological science. The capabilities and potential of TERS are demonstrated by summarising major achievements of TERS applications in disparate fields of scientific research. Finally, ...
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Single molecule detection, sequencing and conformational mapping of aptamers are important for improving medical and biosensing technologies and for better understanding of biological processes at the molecular level. We obtain vibrational signals of single aptamers immobilized on gold substrates using tip-enhanced Raman spectroscopy (TERS). We compare topographic and optical signals and invest...
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ژورنال
عنوان ژورنال: APL Photonics
سال: 2019
ISSN: 2378-0967
DOI: 10.1063/1.5064546